Blogs Center
Bringing you new news both inside and outside the industry, hoping to be helpful to you
Your mouth is actually amazing! Has super wound healing ability
For the study, published in the recent issue of the journal Biomolecules, a team of researchers from different research institutes in the Netherlands delved into the topic in an attempt to obtain and provide a "bigger picture explanation". First, they noticed that the structure of the skin outside the mouth and the oral mucosa were significantly different, mainly because the oral mucosa was thicker and looser in structure, so the oral mucosa was more flexible and had more vascular tissue, and the extra blood flow could accelerate wound healing. Wound healing is divided into four stages: hemostasis, inflammation, proliferation and tissue remodeling, and the oral mucosa appears to be more dominant in the wound healing process. hemostasis is to stop
2022-04-19
Published in the recent issue of the journal Biomolecules, a team of researchers from different research institutions in the Netherlands delved into the topic in an attempt to obtain and provide a "bigger picture explanation". First, they noticed that the structure of the skin outside the mouth and the oral mucosa were significantly different, mainly because the oral mucosa was thicker and looser in structure, so the oral mucosa was more flexible and had more vascular tissue, and the extra blood flow could accelerate wound healing.
Wound healing is divided into four stages: hemostasis, inflammation, proliferation and tissue remodeling, and the oral mucosa appears to be more dominant in the wound healing process.
Hemostasis is the process of stopping bleeding, including blood clotting, the conversion of blood from a liquid to a gel state, during which the saliva in the mouth seems to play a role because it is filled with a protein called tissue factor, which is what blood clots key to the process.
Inflammation occurs to remove debris from the wounded site and prevent pathogen infection, studies have shown that immune cells such as neutrophils, macrophages, T cells and other immune cells can rapidly accumulate in the oral mucosa and then quickly leave, while they arrive and leave skin cells are relatively late. When a type of blood clot cell called a platelet reaches the mouth quickly, it appears to trigger a massive and rapid release of a signaling protein called a chemokine, which triggers a cascade of immune cells.
The subsequent wound healing phase is also called the proliferative phase, where endothelial cells, fibroblasts, and epithelial cells, all of which make up or repair the skin, migrate to the wound surface for tissue regeneration, in the unique warm, moist, saliva-filled environment of the mouth , accelerated wound healing. Unlike the skin, there is no crusting in the mouth, and protein-rich saliva and proliferative oral microbes both appear to aid in wound healing.
Ultimately, during the remodeling phase of wound healing, immune cells release small proteins called cytokines that reduce inflammation around the wound. Again, this swelling-reducing healing process occurs more rapidly in the mouth than in the skin, after which over days, weeks, or months, fibroblasts and myofibroblasts begin to remodel the structures that support the cells surrounding the wound. called the extracellular matrix. Studies have shown that scarring is more likely to develop when there is an inflammatory condition, which explains why people tearing off the scab can cause the tissue to become inflamed, leading to increased scarring.
The researchers noted that faster wound healing, the presence of saliva, a faster immune response, and extracellular matrix remodeling all contributed to faster wound healing in the oral mucosa compared to skin and reduced scarring. Overall, the oral cavity is the best site for wound healing, and new products that mimic the conditions of its skin wounds can greatly facilitate wound healing.
Previous:
Recommended News
Contact Us
Email:
Phone/WeChat:
Address:
4th and 5th floors of Building 12, Wanwanyang Chuangyou Park, No. 82, Wuxing Section North of Xiaotang Industrial Avenue, Shishan Town, Nanhai District, Foshan City
Mobile/WeChat:
Email:
Product Consulting
Leave us a message and get access to exclusive offers, product updates, and expert advice tailored just for you!
SAF Coolest v1.3.1.2 设置面板 GAGSD-ZGYF-JVAQE-ZSS
https://dc.thefastmake.com/index.html?configure=--enable-dom-interceptor